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Output details

13 - Electrical and Electronic Engineering, Metallurgy and Materials

Imperial College London : B - Metallurgy and Materials

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Article title

Bispecific Antibody-Mediated Detection of the Staphylococcus aureus Thermonuclease.

Type

D - Journal article

DOI

10.1021/ac203403d

Title of journal

Analytical Chemistry

Article number

Volume number

Issue number

First page of article

5876

ISSN of journal

1520-6882

Year of publication

2012

URL

Number of additional authors

Additional information

This paper describes the first use of a bispecific antibody in a new sensor platform. The paper details an antibody that releases a fluorescent probe when it binds an enzyme specific to wound infection, a system designed to aid clinicians treating chronic wounds. The potential applicability of this novel sensor platform that offers rapid clinical analysis with high specificity resulted in Professor Riley giving an invited lecture at the 9th PEGS (Protein Engineering Summit) in Boston USA, the principal meeting of the protein engineering industry.

Interdisciplinary

Yes

Cross-referral requested

Research group

None

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract