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Output details

15 - General Engineering

Imperial College London

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Output 13 of 109 in the submission

Article title

Angiogenin induces nitric oxide synthesis in endothelial cells through PI-3 and Akt kinases.

Type

D - Journal article

DOI

10.1021/bi902122w

Title of journal

Biochemistry

Article number

Volume number

Issue number

First page of article

3282

ISSN of journal

1520-4995

Year of publication

2010

URL

Number of additional authors

Additional information

VC-funded research (Ipso Ventures Ltd. ) showed for the first time that angiogenin at physiological concentrations activates nitric oxide synthase. Real-time detection enabled identification of intracellular pathways. Excellent agreement with fluorohistochemical methods taking 24h per slide. Invited keynotes at Electrochem 2011 (Bath), Electrochem 2012 (Dublin). Since applied to cultured tissue and stem cells, published by us in BBA 2010 and Chem. Comm. 2011. Invited to teach the technology at 2nd European Summer School on Nanobiotechnology, Hirschegg, Austria 2011. Continuing work is funded by National Research Foundation of South Africa and Oppenheimer Memorial Trust (#19164/1; £9k and #74699; £23k)

Interdisciplinary

Yes

Cross-referral requested

Research group

None

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract