Output details

Effect of ultrasound on adherent microbubble contrast agents.

Ultrasound molecular imaging with targeted microbubbles offers a potentially powerful tool but lack of understanding of the complex interaction between ultrasound, microbubbles and surrounding environment is hindering further development of the technique. This study has for the first time quantified the effects of ultrasound on individual targeted microbubbles adhering to a wall. The finding offers insights into the complex physics involved, helps with interpretation of imaging results and more importantly can offer guidance on optimal imaging parameters. The work was part of an EPSRC-funded project (EP/G038163/1, 556k) and led to an invited lecture to the EU FP7 workshop COST MP1106.