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Output details

15 - General Engineering

Keele University

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Article title

Chemical and Topographical Effects on Cell Differentiation and Matrix Elasticity in a Corneal Stromal Layer Model

Type
D - Journal article
Title of journal
ADVANCED FUNCTIONAL MATERIALS
Article number
-
Volume number
22
Issue number
17
First page of article
3641
ISSN of journal
1616-301X
Year of publication
2012
URL
-
Number of additional authors
5
Additional information

This paper provides evidence that biochemical and topographic cues can regulate or re-differentiate corneal fibroblasts into the keratocyte lineage. This work was performed with supported from EPSRC CTD (EP/F/500491/1) following on from earlier BBSRC funded studies (BB/F002866/1). The work helped address a clinical opthamology challenge in collaboration with Dr Saaeha Rauz (Birmingham and Midland Eye Centre). This cross-disciplinary training contributed to the PhD award to SL Wilson and her subsequent EPSRC E-TERM landscape fellowship award.

Interdisciplinary
-
Cross-referral requested
-
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-