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Tribology and wear of metal-on-metal hip prostheses: Influence of cup angle and head position

Focuses on the cause of high wear, ion release and failure in metal-on-metal hips. Findings support clinical concerns raised in an MHRA warning (http://www.mhra.gov.uk/home/groups/dts-bs/documents/medicaldevicealert/con079162.pdf, April 2010) relating to clinical consequences of high wear. Co-authored by industry. Study forms one of the first comprehensive systematic assessments of the effects of rotational and translation misalignment of the head and cup on wear of metal-on-metal hips. Findings have been presented at clinical meetings worldwide by two authors (SW/JF) invited to speak as consultants to DePuy International (Isaac, gisaac@its.jnj.com). Laboratory techniques developed have been used to more rigorously test other new bearing materials.