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11 - Computer Science and Informatics

Royal Holloway, University of London

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Article title

An intuitive graphical visualization technique for the interrogation of transcriptome data

Type

D - Journal article

DOI

10.1093/nar/gkr462

Title of journal

Nucleic Acids Research

Article number

Volume number

Issue number

First page of article

7380

ISSN of journal

0305-1048

Year of publication

2011

URL

http://nar.oxfordjournals.org/content/39/17/7380

Number of additional authors

Additional information

<20>The invention presented in this paper is a new visualisation. Instead of visualising a high-dimensional (HD) data simply as a 2D scatterplot, we (automatically) augment the scatterplot with glyphs that indicate near-neighbour relationships in HD space. This 'neighbour-plot' is more expressive than a scatterplot, showing which points in the 2D visualisation are actually close in HD space. Neighbour-plots complement nonlinear dimension-reduction methods by showing where a visualisation is locally correct and where it is misleading. Reearchers at NIMR have shown that these ‘neighbour-plots’ better the existing methods of visualising transcriptome data. (Software is available.)

Interdisciplinary

Cross-referral requested

Research group

B - Computer Learning Research Centre

Citation count

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract