Output details
11 - Computer Science and Informatics
University of East Anglia
Article title
Applying forces to elastic network models of large biomolecules using a haptic feedback device
Type
D - Journal article
Title of journal
Journal of Computer-Aided Molecular Design
Article number
-
Volume number
25
Issue number
3
First page of article
203
ISSN of journal
1573-4951
Year of publication
2011
URL
-
Number of additional authors
2
Additional information
<20> We combine haptic-feedback technology with a popular model for investigating protein flexibility for the first time. This technique can be used to obtain a better understanding of the response of a protein to the binding of a ligand, e.g. a drug molecule, and consequently has applications in the pharmaceutical industry. The Taisho Pharmaceutical Company is working with us to develop the tool for direct use in structure-based drug design. This software is available via www.haptimol.co.uk and is currently being used by researchers interested in protein conformational change.
Interdisciplinary
-
Cross-referral requested
-
Research group
None
Citation count
0
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
