Output details
11 - Computer Science and Informatics
University of East Anglia
Article title
Generation of diverse biological forms through combinatorial interactions between tissue polarity and growth
Type
D - Journal article
Title of journal
PLoS Computational Biology
Article number
e1002071
Volume number
7
Issue number
6
First page of article
-
ISSN of journal
1553-7358
Year of publication
2011
URL
-
Number of additional authors
3
Additional information
<28> Concepts in Turing (1952) underpin mainstream thinking on the autonomous patterning of developing organisms. However the next step, morphogenesis, has proved difficult. Here, we develop perhaps the first computational environment (GFtbox) and associated theory for modelling the development of biological organs under the influence of gene expression patterns,. The ‘growing polarised tissue framework’ enabled us to show how the complex shape of a Snapdragon flower might emerge from a simple shape of a few hundred cells (Output 2).
Interdisciplinary
Yes
Cross-referral requested
-
Research group
None
Citation count
16
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
