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Interspecies comparisons on the uptake and toxicity of silver and cerium dioxide nanoparticles

Little is known regarding manufactured nanoparticle potential toxic effects on human and wildlife. In this work, we compared the potential biological effects of silver and cerium dioxide nanoparticles in a range of cell (human hepatocyte and intestinal and fish hepatocyte) and animal (Daphnia magna, Cyprinus carpio) models to assess possible commonalities in toxicity across taxa. A variety of analytical techniques were employed to characterize the particles and investigate their biological uptake. This work was generated from a collaboration with Edinburgh Napier, Bristol, Exeter and Birmingham Universities. Paper published in Environmental Toxicology and Chemistry.