Output details
11 - Computer Science and Informatics
Royal Holloway, University of London
Article title
A Census of Human Soluble Protein Complexes
Type
D - Journal article
Title of journal
Cell
Article number
-
Volume number
150
Issue number
5
First page of article
1068
ISSN of journal
0092-8674
Year of publication
2012
Number of additional authors
23
Additional information
<28>In this paper we present the largest set of human protein complexes to date. Complexes were identified through a 5-year collaboration between Paccanaro’s lab and the labs of Andrew Emili in Toronto and Edward Marcotte in Austin. The protein interaction networks experimentally identified in Emili's lab were enriched with networks generated through comparative genomics algorithms in Marcotte's lab. We then developed and applied a denoising procedure based on information diffusion, followed by our overlapping clustering procedure to obtain the complexes (ClusterONE). Paccanaro is co-senior and co-corresponding author.
Interdisciplinary
-
Cross-referral requested
-
Research group
B - Computer Learning Research Centre
Citation count
31
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
