You are in : Home » Results & submissions » Select UOA » 15 - General Engineering » View submission: Brunel University London » Outputs » Detail

Output details

15 - General Engineering

Brunel University London

Return to search Previous output Next output

Output 128 of 258 in the submission

Article title

Gradient elution in counter-current chromatography: A new layout for an old path

Type

D - Journal article

DOI

10.1016/j.chroma.2011.02.052

Title of journal

Journal of Chromatography A

Article number

Volume number

1218

Issue number

First page of article

6053

ISSN of journal

00219673

Year of publication

2011

URL

http://pdn.sciencedirect.com/science?_ob=MiamiImageURL&_cid=271409&_user=545641&_pii=S0021967311002792&_check=y&_origin=article&_zone=toolbar&_coverDate=09-Sep-2011&view=c&originContentFamily=serial&wchp=dGLbVlV-zSkWb&md5=faae4b365ef6114ad6298d1fa12a0ffa&p

Number of additional authors

Additional information

This is the first time gradient elution has been applied in method development for Counter-current Chromatography (CCC) greatly expanding the polarity range for the separations being performed. It is also the first time a correlation between partition coefficient values, phase system polarity and elution profile has been established. This has led to an AstraZeneca CASE EPSRC Industrial studentship on rapid method development and to the application of CCC gradient methods for novel applications for industry to speed up method development (Dr Paul Hellier, Responsable Développement Industriel, Pierre Fabre, France – paul.hellier@pierre-fabre.com).

Interdisciplinary

Cross-referral requested

Research group

None

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract