Output details
15 - General Engineering
University of Hertfordshire
Nano-Ag inhibiting action potential independent glutamatergic synaptic transmission but increasing excitability in rat CA1 pyramidal neurons
-International collaborative research into nano-Ag’s functionality-toxicity in rat CA1-pyramidal-neurons which control feeling, memory and mode of all mammalian lives.
-Effects of nano-dosage incrementally increased excitability in rat CA1 pyramidal neurons, confirming again the safety threshold of 0.05 wt.% in the nano-suspension.
-The toxicity safety mechanism level was defined, which is of concern for most for nano-applications (over £1billion global investment during past 10 years).
-The significance is that this research paper gave evidence to prove a minimum-dosage-window exists (0.05wt.%) for a guaranteed safe-use of nano-particles.
-Led to a breakthrough in the use of nanomaterial-nanotechnology in bio-medical-healthcare applications.