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15 - General Engineering

Keele University

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Article title

Direct transplantation of mesenchymal stem cells into the knee joints of Hartley strain guinea pigs with spontaneous osteoarthritis

Type

D - Journal article

DOI

10.1186/ar3735

Title of journal

ARTHRITIS RESEARCH & THERAPY

Article number

ARTN R31

Volume number

Issue number

First page of article

ISSN of journal

1478-6354

Year of publication

2012

URL

http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000304698800045&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=65c2c6c1224a08d1a3198315ff59119e

Number of additional authors

Additional information

Being invited to be a co-author on this paper demonstrates the international standing of SR in the field of cell therapy and its use in treating osteoarthritis (OA). This ‘highly accessed’ paper demonstrates that a paradigm shift in delivering cell therapy to osteoarthritic joints is possible, that mesenchymal stem cells when injected into a knee with OA (rather than via open surgery), can elicit repair. Dr Uchida (an orthopaedic surgeon) requested to visit our laboratory for 3 months in 2011 to continue collaborations between our groups in Japan and UK, which has resulted in several publications (eg doi:10.1007/s00586-011-1971-7 and 10.1186/1471-2202-11-84).

Interdisciplinary

Yes

Cross-referral requested

Research group

None

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract