Output details
12 - Aeronautical, Mechanical, Chemical and Manufacturing Engineering
Loughborough University
Article title
A plant-wide dynamic model of a continuous pharmaceutical process
Type
D - Journal article
Title of journal
Industrial and Engineering Chemistry Research
Article number
-
Volume number
51
Issue number
47
First page of article
15393
ISSN of journal
0888-5885
Year of publication
2012
URL
-
Number of additional authors
2
Additional information
The work relates to the development of a plant-wide dynamic model of the first integrated end-to-end continuous pharmaceutical manufacturing pilot plant developed at MIT. The model enabled the evaluation of different recycling and start-up strategies, which provided tools to design cost effective and environmentally friendly processes. The work opened up new opportunities to develop plant-wide control and Quality by Design strategies for the pilot plant. As a result, it contributed to the renewal of the Novartis-MIT project and gave me the opportunity to win the best contribution award within Novartis-MIT center for continuous manufacturing.
Interdisciplinary
-
Cross-referral requested
-
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
