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Output details

13 - Electrical and Electronic Engineering, Metallurgy and Materials

University of Oxford

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Output 39 of 136 in the submission

Article title

Extracellular matrix production by adipose-derived stem cells: Implications for heart valve tissue engineering

Type

D - Journal article

DOI

10.1016/j.biomaterials.2010.09.003

Title of journal

Biomaterials

Article number

Volume number

Issue number

First page of article

119

ISSN of journal

0142-9612

Year of publication

2011

URL

Number of additional authors

Additional information

This paper is one of a series from a long standing collaboration with Professor Magdi Yacoub’s group. Three different human cell types were seeded on Type 1 collagen based scaffolds (HIVs, MSCs and ADSCs), and ADSCs shown to produce more tissue more quickly and closer to that required to generate a heart valve. This is important because it shows that different stem cells behave differently even with the same stimulus and that ADSCs may prove the best cell line to use. The use of reproducible and specifically tailored scaffolds from Oxford was critical in the success of this study.

Interdisciplinary

Cross-referral requested

Research group

None

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract