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Output details

15 - General Engineering

Brunel University London

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Article title

Study of tumor blood perfusion and its variation due to vascular normalization by anti-angiogenic therapy based on 3D angiogenic microvasculature

Type

D - Journal article

DOI

10.1016/j.jbiomech.2009.01.009

Title of journal

Journal of Biomechanics

Article number

Volume number

Issue number

First page of article

712

ISSN of journal

00219290

Year of publication

2009

URL

http://pdn.sciencedirect.com/science?_ob=MiamiImageURL&_cid=271132&_user=545641&_pii=S0021929009000281&_check=y&_origin=article&_zone=toolbar&_coverDate=16-Apr-2009&view=c&originContentFamily=serial&wchp=dGLzVlV-zSkWb&md5=ef66d38c8ac3d675401e9e9d700550b6&p

Number of additional authors

Additional information

This output is a result of our long term collaboration with Prof Xu’s group in Fudan University, China pioneering tumour angiogenesis modelling focusing on the micro vessel network generation. The contributions of this output were the development of 3D network generation and the coupled calculation of blood perfusion. In addition, the influence of anti-angiogenesis drugs on the network evolution was also investigated. The major milestone this highly cited work provided, is a platform for the investigation of tumour drug treatment. It is now regarded as one of the classical works (Bottaro and Ansaldi, J Biomed Eng, 2012Aug; 134(8):084501).

Interdisciplinary

Cross-referral requested

Research group

None

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract