Output details

Stress Analysis of Carotid Atheroma in Transient Ischemic Attack Patients: Evidence for Extreme Stress-Induced Plaque Rupture

This output was a result of a BHF project in collaboration with Professor Gillard of Cambridge University. Based on the MR images, provided by the Cambridge group, of a patient with a recent rupture of carotid arterial atherosclerotic lesion, the study reconstructed the rupture site local to mimic the pre-rupture status. With a total of 16 reconstructed models of different combinations of local structure, the simulation results indicated that high local wall tensile stress is the main reason for the rupture. This study further demonstrated the role of stress on lesion rupture from some clinic evidences which are rarely available.