Impact (REF3a/b)

Impact template (REF3a)

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All impact case studies

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Individual case studies

20 Year Landmark Aortic Trials Produce National and International Guidelines and Alter Patient Management (70K)

Acrobot: Active Constraint Robots Improve Outcome in Arthritis Surgery (113K)

Blood Pressure and Lipid-Lowering Treatment: Impact on Cardiovascular Outcomes and Influence on Guidelines (112K)

Building a Safer Surgical Workforce; Driving Innovation in Simulation, Training & Educational Research (51K)

Clinical Development of Temozolomide: An Anticancer Drug that Improves Survival of Patients with Brain Cancer (Glioma) (66K)

Creation of Thiakis Ltd and Profitable Sale to Wyeth Ltd. (57K)

Defining the Role of Antiretroviral Therapy for Primary or Recent HIV Infection (73K)

Developing unique conjugation (PEGylation) technology and commercial spinout through PolyTherics Ltd. (100K)

Development of a Rational Framework to Evaluate the Toxicity of Drugs and Chemicals in Food and the Environment. (158K)

Development of Beta Blockers for the Treatment of Heart Failure (119K)

Development of Long-Acting Anticholinergics (e.g. tiotropium bromide) for the Treatment of Chronic Obstructive Pulmonary Disease (104K)

Development of Novel Technologies for Radiofrequency Assisted Surgical Resection (157K)

Development of Novel Therapies to Treat Severe Airway Disease (155K)

Discovery that Harmonic Ultrasound Modes using Microbubbles can Differentiate Benign from Malignant Liver Tumours, Producing a Major Improvement in Outcome (151K)

Driving the Prevention of Occupational Asthma (86K)

Eliminating Death from Heart Failure in Thalassaemia Major Using T2* Cardiovascular Magnetic Resonance (146K)

Exhaled Nitric Oxide as a Non-Invasive Biomarker of Lung Inflammation (77K)

Fewer Men Now Required to be Tested for Non-Gonococcal Urethritis (78K)

HIV Associated Multicentric Castleman’s Disease: Translating Biology to Improved Patient Survival (148K)

Improved Life Expectancy with Fewer Side-Effects in Breast Cancer Using an Innovative Switching Strategy (109K)

Improved Treatment of Balance Disorders (61K)

Improvement in Diagnosis and Management of Tuberculosis in Children. (131K)

Improving Outcomes for Patients with Gestational Trophoblastic Disease (GTD) (67K)

Improving Quality for Cardiovascular Disease Prevention in Europe and the National Health Service (68K)

Improving the Safety and Quality of Healthcare Delivery Using Routine Data (90K)

Introduction of Mass Screening by Once-Only Flexible Sigmoidoscopy in the English Bowel Cancer Screening Programme to Reduce Colorectal Cancer Incidence Rates (92K)

Invention and Development of a Globally Recognised Molecular Method of Monitoring Disease Response in Chronic Myeloid Leukaemia (66K)

Major Advance in Identification and Treatment of HIV-1 Tuberculosis Immune Reconstitution Inflammatory Syndrome (TB-IRIS): A Common and Serious Complication of Antiretroviral Therapy (70K)

Making Surgery Safer: the WHO Surgical Safety Checklist (194K)

Positive Impact of Non-invasive Ventilation on Survival in Duchenne Muscular Dystrophy and Related Neuromuscular Disorders (61K)

Progression of the Imperial College Spin-out “Circassia” to a Multimillion Pound Specialty Biotechnology Company (95K)

Sublingual Allergen Immunotherapy in the Treatment of Hayfever (160K)

The Introduction of a Successful Treatment of Pulmonary Arterial Hypertension in Adults (114K)

Threefold Increase in the Use of Anti-TNF in the Treatment of Common Chronic Inflammatory Conditions (151K)